Nano Gel Transdermal Patch Development

In the evolving field of drug delivery systems, CD Formulation leads with advanced nano gel transdermal patches. This innovative solution provides a non-invasive, efficient, and precise method of drug delivery, enhancing drug stability and absorption. We specialize in the development and customization of nano gel transdermal patches to meet diverse research needs.

About Nano Gel Transdermal Patches

Nano gels, also known as hydrogel nanoparticles or gels composed of nanoparticles, are nanosized three-dimensional cross-linked (physical or chemical) polymer networks. They are viscoelastic, and their internal structure is similar to that of hydrogels. Nanogels have excellent properties, including size tunability, homogeneity, stability, low toxicity, response to stimuli (temperature, light, pH, enzymes, etc.), and good drug encapsulation ability. Because of these properties, nanogels can serve as potent carriers for a variety of drug delivery applications and are a promising new drug delivery system.

Fig.1 (a) Typical nanogel structure developed via inverse emulsion polymerization method. (b) Morphology of chitosan-based nanogels loaded with myricetin. (Panoraia I. Siafaka, et al. 2023)

Our Nano Gel Transdermal Patch Development Services

Nano Gel Materials

Customizable Nano Gel Carriers

• Size-specific nanocarriers: Specific-size nanocarriers are more suitable for skin and transdermal drug delivery. For example, the accumulation of nanogels with small (<100 nm) and rigid core structures in the stratum corneum is preferable to liposomes because rigid nanogels can join within the cellular space.
• Amphiphilic nano gels: The surface charge of nanogels affects protein binding and cellular uptake. Amphiphilic nanogels are a hydrophilic polymer matrix containing hydrophobic groups, which can be used as innovative carriers of hydrophobic drugs. The amphiphilicity of nano gels can affect skin delivery, so balancing the network composition with suitable surface hydrophobicity and low network stiffness can enhance skin penetration.
• Cyclodextrin-based nano gels: These gels show minimal skin irritation and demonstrate good permeability when incorporated into hydroxypropyl methylcellulose (HPMC) matrices.

Types of Nano Gels We Can Develop

• Temperature-sensitive nano gels: Respond to temperature changes for controlled drug release. These smart materials can modulate drug release rates based on body temperature. For instance, at body temperature, the gel could remain, gradually releasing the drug. If the temperature rises, the gel could collapse, releasing the drug more rapidly.
• pH-sensitive nano gels: Adapt to pH variations, making them suitable for targeted drug delivery, biosensing, and other biomedical applications. These nano gels undergo a reversible change in their physical state, such as swelling or shrinking, depending on the pH of their environment.

Our Nano Gel Preparation Techniques

We utilize several advanced techniques to prepare nano gels, ensuring precise control over particle size, monodispersity, and formulation characteristics. Our methods include:

Precipitation Polymerization/Cross-Linking

• Efficiently forms larger gel structures.
• Suitable for applications requiring bulk gel formation with robust properties.

Inverse Emulsion Polymerization/Cross-Linking

• Produces nano gels with uniform particle sizes.
• Ideal for creating nano gels with consistent properties across batches, ensuring reliability in research and development applications.

Soap-Free Emulsion Polymerization

• Achieves high monodispersity and precise control over particle sizes.
• Ensures purity by eliminating the need for surfactants, making it suitable for sensitive drug delivery applications.

Fig.2 Our Nano Gel Preparation Methods. (CD Formulation)

Why Choose CD Formulation?

• Custom Drug Release Profiles: We design nano gels for sustained, controlled, or targeted drug release, offering tailored solutions to meet specific research needs.
• Flexible Formulation Options: Our expertise in nano gel customization enables us to deliver active ingredients, including small molecules, peptides, and proteins, ensuring versatility in drug development.
• Expertise in Nanotechnology: With extensive experience in nanotechnology and transdermal systems, our team ensures effective and reliable product outcomes through optimized formulations.

Published Data

Our commitment to research and development ensures the safety, efficacy, and convenience of nano gel transdermal patches. If you're interested in customized transdermal solutions, please contact us, and our team will respond within three business days.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.