Metal Nano Transdermal Patch Development

At CD Formulation, we lead in cutting-edge transdermal technology through our metal nano transdermal patch development services. Utilizing the unique properties of metal nanoparticles, we provide innovative solutions to enhance the effectiveness, precision, and convenience of active ingredient delivery through the skin.

About Metal Nano Transdermal Patches

Metal nano transdermal patches are patches embedded with metal nanoparticles that facilitate the delivery of active pharmaceutical ingredients (APIs) through the skin. Metal nanoparticles used can include materials such as silver, gold, or zinc. Metal nanoparticles have unique properties such as high surface area-to-volume ratio, surface plasmon resonance, and enhanced permeability, which contribute to their effectiveness in drug delivery. The metal nanoparticles can penetrate the skin barrier more effectively than larger particles, allowing for deeper and more efficient delivery of Apis. The integration of metal nanoparticles can be designed to provide controlled or sustained release of the active ingredients, improving effects and minimizing the need for frequent applications.

Fig.1 Topically applied Au-based SNAs for wound healing and early scar diagnosis. (A) Schematic of Au-SNA carrying GM3S siRNA and ethylene glycol (GM3S SNAs). (B) Efficacy of GM3S SNAs in down-regulating cutaneous GM3S mRNA and protein levels in an obese mice model. (C) GM3S SNAs prevent the delayed wound healing in the obese mouse. (D) Early, facile detection of abnormal scarring through topical application of SNA Nanoflare. (E) SNA Nanoflare targeting connective tissue growth factor (CTGF) mRNA revealed the presence of HSFs in ex vivo skin, relative to NDFs or drug-treated HSFs. (Lijun Liu, et al. 2023)

Advantages of Metal Nano Transdermal Patches

Fig.2 The Advantages of Metal Nano Transdermal Patch. (CD Formulation)

• Enhanced Bioavailability: Metal nanoparticles can enhance the solubility and stability of APIs, leading to better absorption and bioavailability.
• Targeted Delivery: The precise control over nanoparticle size and surface properties allows for targeted delivery to specific skin layers or conditions.
• Faster Onset of Action: Due to improved skin penetration and absorption, metal nano patches can provide quicker effects compared to traditional methods.
• Reduced Side Effects: By delivering drugs directly through the skin, these patches can minimize systemic side effects associated with oral or injectable medications.

Applications of Metal Nano Transdermal Patches

Our Metal Nano Transdermal Patch Development Services

Formulation and Design

• Nanoparticle Selection: We choose the appropriate metal nanoparticles (e.g., silver, gold, zinc) based on the desired drug delivery profile and compatibility with APIs.
• Patch Matrix: We design a matrix that ensures nanoparticle integration while maintaining adhesive properties and user comfort.

Manufacturing Process

• Nanoparticle Fabrication: Utilizing methods such as chemical reduction, physical vapor deposition, and laser ablation to create nanoparticles with precise properties.
• Integration: Embedding nanoparticles into the transdermal patch matrix using techniques like solvent casting or co-extrusion.

Our Testing and Quality Control

Why Choose CD Formulation?

• Tailored R&D Solutions: Our team collaborates closely with researchers to develop customized formulations, focusing on enhancing drug solubility, stability, and delivery efficiency. We offer precise design and optimization of microemulsion and nanoemulsion systems to meet specific research requirements.
• Advanced Manufacturing Capabilities: We provide scalable solutions, ensuring high-quality, consistent results for various R&D projects. Our facilities utilize cutting-edge technology to meet diverse research needs.
• Continuous Innovation: Based on the latest advancements and market trends, we continually refine our formulation techniques, ensuring that our solutions remain at the forefront of transdermal technology.

Published Data

Our innovative microemulsion and nanoemulsion transdermal patch development services are dedicated to enhancing the efficacy and ease of medication administration via the skin. These patches are engineered using sophisticated emulsion techniques that optimize the penetration, stability, and bioavailability of active pharmaceutical ingredients (APIs), marking a significant advancement in drug delivery systems. For inquiries about our services or to discuss your specific needs, please contact us. Our team will respond within three working days.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.