Matrix Transdermal Patch Development

At CD Formulation, we are dedicated to pioneering advancements in matrix transdermal patch technology. With a multidisciplinary team of pharmaceutical scientists, engineers, and regulatory experts, we strive to develop innovative solutions that meet the evolving needs of the healthcare industry. With over 20 years of experience in formulation development, we provide professional and customized matrix transdermal patch development services.

About Matrix Transdermal Patches

Fig. 1. Drug matrix in adhesive. (Disha A Deulkar, et al. 2024)

A matrix transdermal patch is a patch used for transdermal drug delivery. The drug is embedded within a matrix or reservoir. The drug is released through the skin at a controlled rate, which is determined by the composition of the matrix and other factors. The backing layer is usually made of materials like polyester or polyethylene, it provides structural support. The adhesive layer helps the patch adhere to the skin and prevents drug leakage.

Advantages of Matrix Transdermal Patches

Matrix transdermal patches offer several advantages over traditional oral medications or injections, including:

Fig.2 Advantages of Matrix Transdermal Patch (CD Formulation)

• Convenience: Easy to apply and remove.
• Steady Drug Levels: Provides consistent medication release, potentially improving therapeutic outcomes and reducing side effects.
• Patient Compliance: Requires less frequent dosing.
• Reduced Side Effects: Minimizes gastrointestinal irritation and systemic side effects by bypassing the digestive system.

Our Matrix Transdermal Patch Development Process

Matrix Design

Determine the composition of the matrix that will hold the drug and control its release rate. This includes selecting polymers or other materials that are biocompatible and provide the desired release profile.

Compatibility Testing

Assess the compatibility of the drug with components of the patch (e.g., polymers, adhesives) to ensure stability and efficacy.

Layer Construction

Design the layers of the patch (backing layer, drug-containing matrix, adhesive layer) to optimize drug release kinetics and adherence to skin.

Biodegradable Matrices

Development of biodegradable polymers and matrices that dissolve or degrade after drug delivery, minimizing waste and environmental impact.

Innovative Technology for Transdermal Systems

We have established an advanced research and development platform for transdermal drug delivery technology, including the study of drug transdermal absorption mechanism, the development of new transdermal accelerators, and the optimization of controlled release technology, which can continuously promote the technological innovation of matrix transdermal patches. Including but not limited to:

• Nano-formulations: Utilizing nanotechnology to enhance the permeability of drugs through the skin barrier, improving bioavailability and reducing patch size.
• In Vitro Release Studies: Testing the patch in laboratory settings to measure drug release profiles under various conditions.
• In Vivo Pharmacokinetic Studies: Conducting studies in animals or humans to evaluate drug absorption, distribution, metabolism, and excretion following patch application.

Why Choose Us for Matrix Transdermal Patch Development?

• Customized Development Services: We tailor matrix transdermal patch development to meet individual needs, including drug formulation optimization, patch size adjustment, and special material selection.
• Safety Assessments: We ensure the clinical safety of matrix transdermal patches through rigorous skin irritation and allergy tests.
• Continuous Innovation: We are committed to developing more efficient, safer, and eco-friendly matrix transdermal patches.

Published Data

Our company boasts a strong R&D team and advanced formulation technology. We develop formulations and preparation processes suitable for skeletal transdermal patches based on the physical and chemical properties of different drugs. By optimizing the drug release mechanism, we ensure continuous and steady drug delivery into the bloodstream through the skin. Contact us with your needs, and our colleagues will reach out to you within three working days.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.