Active Gel Transdermal Patch Development

At CD Formulation, we specialize in pioneering solutions for advanced transdermal drug delivery through our cutting-edge active gel transdermal patch technology. With a commitment to innovation, quality, and client-centric solutions, we empower research organizations to develop effective treatments for various therapeutic needs.

About Active Gel Transdermal Patches

An active gel transdermal patch is a specialized type of transdermal delivery system designed to administer active ingredients through the skin for therapeutic purposes. Our Active Gel Transdermal Patches are designed with precision and efficacy in mind. Utilizing state-of-the-art formulation techniques, we create gel matrices that optimize the delivery of active pharmaceutical ingredients (APIs) through the skin. This technology ensures controlled release profiles, maintaining therapeutic levels of medications over extended periods, and enhancing patient compliance.

Structure of Active Gel Transdermal Patches

Transdermal delivery mechanism of gel transdermal patch: The active ingredients in the gel matrix diffuse through the skin's layers and enter the bloodstream, bypassing the gastrointestinal tract. This route of administration offers advantages such as avoiding first-pass metabolism in the liver and providing a steady, controlled release of the drug.

• Backing Layer: Provides structural support to the patch.
• Gel Matrix: Contains the active ingredients and controls their release. The gel may include various excipients to enhance stability, permeability, and adhesion.
• Adhesive Layer: Ensures the patch adheres firmly to the skin during wear, facilitating continuous delivery of the APIs.

Our Active Gel Transdermal Patch Development Services

We can develop a wide range of active gel transdermal patches for a wide range of therapeutic applications:

• Pain Management: Delivering analgesics directly to the site of pain for rapid relief.
• Hormone Replacement Therapy (HRT): Providing controlled release of hormones to manage menopausal symptoms and hormone deficiencies.
• Cardiovascular Health: Administering medications for hypertension and angina with consistent efficacy.
• Neurological Disorders: Delivering drugs for conditions like Parkinson's disease and epilepsy for improved patient outcomes.
• Dermatological Conditions: Treating skin disorders or delivering cosmetic agents.

Workflow for Active Gel Transdermal Patch Development

1. Initial Consultation: We understand your specific requirements and research goals.
2. Formulation Development: Utilizing advanced techniques, we create prototypes of the gel matrices.
3. Evaluation and Testing: Conduct rigorous in vitro and in vivo studies to ensure efficacy and safety.
4. Optimization and Scaling: Refine the formulation process and scale up production.

Our Innovative Technology and Testing

Stability Studies

We conduct comprehensive stability studies to assess the physical, chemical, and microbiological stability of the patches over their shelf life. Factors such as temperature, humidity, and light exposure are evaluated to ensure product integrity.

In Vitro and In Vivo Testing

Fig.1 Schematic representation of Franz-diffusion cell. (Marta Slavkova, et al. 2023)

• In Vitro Studies: We assess the release kinetics of APIs from the gel matrix using diffusion cells or Franz cells. These studies provide insights into the patch's performance under controlled conditions.
• In Vivo Studies: We conduct animal studies to evaluate pharmacokinetics, tissue distribution, and systemic effects of the APIs delivered via transdermal patches. These studies help validate efficacy and safety profiles before human trials.

Why Choose CD Formulation?

• Innovative Formulation Expertise: Our team of scientists and researchers are leaders in developing gel matrices that maximize API bioavailability and skin permeability.
• Customized Solutions: We collaborate closely with pharmaceutical partners to tailor patches for specific therapeutic needs.
• Quality Assurance: Rigorous testing and adherence to global regulatory standards guarantee that our patches meet the highest quality and safety benchmarks.

Published Data

Our company has a unique technical advantage in active gels and can develop gel substrates with high drug loading, good stability, and transdermal properties. This gel matrix can effectively encapsulate drug molecules and improve drug stability and bioavailability. Work with our experienced team to innovate and develop customized patches tailored to your product pipeline. If you have any needs, please do not hesitate to contact us, and our colleagues will contact you within three working days.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.