Sleep Oral Thin Film Formulation Research

Oral thin films replace the need for pills, powders, or liquid supplements for personal wellness products. CD Formulation develops customized oral thin film delivery systems for sleep disorder improvement, delivering advanced R&D support to meet research and development demands.

Fig.1 The preparation steps of the melatonin-loaded (MOF) orodispersible films.
(Fabio Tamanini, et al., 2024)

Advantages of Sleep Oral Thin Films

• Dissolve quickly and deliver a precise dose, helping people fall asleep faster and wake up feeling refreshed.
• Packaged in a compact, carry-on size container, these strips are perfect for travel, camping trips, or for those who need a quick and easy solution for better sleep.
• Medically proven fast absorption. Rapid remedy for insomnia, jet-leg fatigue and insufficient sleep.
• Sleep soundly, anywhere, anytime with sleep oral thin film - no water needed.

Applications of Sleep Oral Thin Films

The oral thin film can be used as a delivery carrier to deliver some sleep-promoting ingredients. When the oral thin film contacts saliva, it quickly disintegrates and releases the active ingredients, and takes effect quickly, becoming an alternative to pills, powders, and liquid preparations. Our R & D team uses oral thin film as a carrier to load some sleep ingredients to prepare the sleep oral thin film, helping people with sleep disorders relieve sleep disorders.

Applications	Detailed Information
Sleep-promoting ingredients	Ingredients that can be loaded through oral thin film include but are not limited to: Melatonin Valerian Extract Tryptophan Theanine Passionflower Gamma-aminobutyric acid
Oral thin films as a delivery system for melatonin Fig.2 An oral delivery platform based on orodispersible films. (Umberto M. Musazzi, et al., 2019)	Active Ingredients: Melatonin This study aimed to investigate the feasibility of innovative ODFs as a delivery system for melatonin that can either decrease the sleep onset latency or increase the total sleep time, suitable for people with swallowing difficulties such as children and the elderly. In the attempt to guarantee both a fast onset of action and a prolonged release, different ODF formulations containing melatonin-loaded lipid microparticles and the free-dispersed drug were studied.

Our Sleep Oral Thin Film Formulation R&D Services

We have a wide range of mature sleep oral thin film formulations, and they are formulated specifically to promote deep and healthy sleep cycles without giving you a sleepy hangover in the morning. Whether you want to use our existing formulations or develop new ones, we can provide one-stop solutions. Our sleep oral thin film development process includes formulation development, process development, characterization, manufacture, and packaging.

Fig.3 Development process of sleep oral thin film. (CD Formulation)

Formulation Development: Including formulation design, API and excipients ingredient screening, API-excipients compatibility study, etc.

Process Development: Including preparation method screening, process parameter optimization.

Characterization: Including appearance and physicochemical characterization and the evaluation of biological properties.

Manufacture: We have different scales of production equipment that can meet customers' production needs.

Packaging: Our packaging includes packaging material selection, package printing, multiple packaging specifications selection, etc.

Our Sleep Oral Thin Film Characterization Services

We have a team of skilled professionals with extensive experience in conducting mechanical properties characterization specifically tailored for oral thin films. Our advanced equipment and testing methods can accurately assess key parameters of sleep oral thin film, helping our customers enhance the formulation development research and commercialization of oral thin film products.

Why Choose CD Formulation?

• We specialize in developing oral thin film formulations research for treating sleep disorders, tailored to specific research requirements.
• With extensive knowledge and expertise in drug delivery systems, we ensure that our oral thin films effectively deliver sleep medications reliably and consistently.
• Our advanced taste-masking technology can improve the palatability of oral thin films, enhancing people acceptance and compliance.

Our team of experienced researchers and scientists can support all stages of oral thin film development research services, from formulation development to scale-up and commercialization. If you require our sleep oral thin film services, please contact us by phone or email, and our colleagues will get back to you within three working days.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.