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Oral Thin Film Thickness Testing

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Thickness testing is a key quality control index for the consistency and effectiveness of oral thin film products. Through thickness testing, the content of active ingredients can be effectively evaluated, which has important guiding significance for accurate clinical medication, product performance, and patient safety. CD Formulation provides a variety of oral thin film thickness testing methods to meet different types of film thickness testing needs.

Importance of Oral Thin Film Thickness Testing

The thickness of oral thin films impacts content, drug release, solubility, patient acceptance, etc.

Fig.1 The Benefits of Measuring Oral Thin Film Thickness. Fig.1 The Importance of Oral Thin Film Thickness Testing. (CD Formulation)

Our Oral Thin Film Thickness Testing Services

Our oral film thickness testing procedure generally includes the following steps:

Sample Check

For the detection of the thickness of the oral thin film, in order to ensure the accuracy of the test results, we require the film to be complete and without creases. After receiving the sample from the customer, we first check the appearance of the film to ensure the accuracy of the test results.

Test Point Selection

Our oral thin film thickness testing is conducted by measuring film at a few different locations, such as measuring 1 central point and 4 corners, each point is tested three times to obtain the average value. We can also select test points according to customer requirements.

Testing Method Selection

Our oral film thickness testing methods include direct measurement and indirect measurement, we select the appropriate testing method according to oral thin film type, requirements and budget.

Our Capabilities for Testing Oral Thin Film Thickness

Testing Instrument	Detailed Information
Screw Gauge Micrometer	Screw gauge micrometer, also known as a micrometer screw gauge, is a more precise measuring tool than the vernier caliper, using it to measure the length can be accurate to 0.01mm, which is one of the methods we use to measure the thickness of oral thin film.
Digital Caliper	The digital caliper (sometimes incorrectly called the digital vernier caliper) is a precision instrument that can be used to measure internal and external distances extremely accurately.
Thickness Tester	Thickness tester is a high-precision mechanical contact method thickness tester, which can be used for thickness measurement of thin films, etc. This instrument conforms to standards for mechanical contact method. The pressure foot can be lifted and lowered automatically, which can minimize the errors caused by human operation.
Electron Microscope Measurement	Scanning electron microscope (SEM) and transmission electron microscope (TEM) are the main thickness measuring instruments of electron microscopy. We measure the thickness according to the scanning image of the cross-section of the film.
Laser-Based Testing	Laser systems can be used to quickly and accurately measure the thickness of materials by analyzing the reflection or refraction of a laser beam.

Our Advantages in Testing Oral Thin Film Thickness

Accuracy: Our oral thin film thickness testing uses advanced equipment and technology to provide precise and accurate measurements of film thickness, ensuring reliable results.
Expertise: Our team of professionals has the knowledge and expertise to accurately conduct and interpret oral thin film thickness testing, providing valuable insights for product.
Non-destructive Testing: We can provide a non-destructive testing method, meaning it does not alter or damage the oral thin film in any way, allowing for continued use of the product after testing.
Efficiency: Our testing process is efficient and quick, providing results in a timely manner, and allowing for faster decision-making and production processes.

Published Data

Technology: Digital Vernier Calliper

Journal: PHARMA SCIENCE MONITOR

IF: 0.5

Published: 2013

Results: In this study, the thickness of the film was measured using a digital vernier calliper with a least count of 0.01 mm at different spots of the film. The thickness was measured at three different spots of the film and average was taken and Standard Deviation was calculated. As all the formulations contain different amounts of polymers, hence the thickness gradually increases with the number of polymers. All the film formulations were found to have a thickness in the range of 0.05 mm to 0.15 mm.

Fig.2 Evaluating Consistency in Oral Thin Film Formulation Batches. Fig.2 Oral thin film of different formulation batches. (Yatin D. Kapadia, et al., 2013)

CD Formulation is very experienced in oral thin film thickness testing, providing professional testing instruments and testing methods, which can accurately measure the thickness of oral thin film. If you have a requirement about our oral thin film thickness testing services, please contact us by phone or email, and our colleagues will reply to you within three working days.

References

Yatin D. Kapadia, Hiten P. Sodha, et al. FORMULATION DEVELOPMENT AND EVALUATION OF SUBLINGUAL FILM OF ASENAPINE MALEATE. PHARMA SCIENCE MONITOR. 2013, Vol (4):190-209.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.

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