Oral Thin Film Swelling Properties Testing

Swelling is an indicator of the expansion of the oral thin film, which is the expansion of the film sample placed in a specified solvent at a certain time and temperature, which can affect the disintegration and dissolution of the film in the mouth, and then affect the drug release and clinical efficacy. With many years of experience in the development of oral thin films, CD Formulation provides professional swelling properties testing to accelerate the development of oral thin films for customers.

Fig.1 Swelling behavior of metoclopramide swellable oral thin film at different times. (Marzia Alam, et al., 2014)

Importance of Oral Thin Film Swelling Properties Testing

• Swelling properties of oral thin film directly impact the thin film's disintegration and dissolution rates, which in turn affect the bioavailability of the thin film.
• Swelling properties testing can help to identify any potential issues such as inadequate disintegration or incomplete dissolution, which could impact the efficacy and safety of the product.

Our Oral Thin Film Swelling Properties Testing Services

The swelling characteristics of oral thin films are measured in terms of percent hydration. Briefly, films of specific sizes are accurately weighed and stored on a stencil. The films were immersed along with the nets in simulated saliva or relevant swelling medium maintained at a specific temperature. The net is removed from the saliva medium at various time intervals, the film is wiped and re-weighed, and finally, the percentage hydration is determined by a specific formula.

Fig.2 Process of Oral Thin Film Swelling Properties Testing. (CD Formulation)

Our Capabilities for Testing Oral Thin Film Swelling Properties

• High-precision thermostatic bath.
• Automatic internal calibration electronic balance.
• Digital Vernier Calipers.
• Electron microscope.
• Various buffers and simulated saliva.
• ...

Our Advantages in Testing Oral Thin Film Swelling Properties

• Accurate Assessment: Our testing method provides an accurate assessment of the swelling properties of oral thin films, helping to determine their ability to rapidly dissolve and release active ingredients.
• Comprehensive Analysis: Our testing covers a wide range of parameters, including thickness, in vitro swell ratio, and disintegration time, providing a comprehensive analysis of the swelling properties of oral thin films.
• Expertise and Experience: Our team of scientists and researchers have extensive expertise and experience in swelling properties testing of oral thin films, ensuring reliable and accurate results.
• Cost-effective Solutions: We offer cost-effective testing solutions, providing high-quality results at competitive prices.

Published Data

Swelling properties testing of oral thin films is a fundamental step in the development and evaluation of oral thin films. CD Formulation provides comprehensive oral thin film swelling properties testing solutions to help customers optimize formulas, improve drug delivery, and ensure the overall effectiveness of the product. If you have a requirement about our oral thin film swelling properties testing services, please contact us by phone or email, and our colleagues will reply to you within three working days.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.