Here's how you can reach us...
  • Tel:
  • Email:

Oral Thin Film Folding Endurance Testing

Inquiry

Oral thin film folding endurance testing is a process used to evaluate the ability of thin film formulations to withstand repeated folding without breaking or damage, and this testing is important in the development of oral thin film medications, as these products need to be able to withstand the stresses of handling and transportation without compromising their integrity. The highly qualified analysis team at CD Formulation utilizes advanced equipment to deliver accurate oral thin film folding endurance testing results, which aids in advancing research on oral thin film products.

Importance of Oral Thin Film Folding Endurance Testing

  • Good folding endurance can withstand the handling and packaging stresses during the production and distribution of oral thin film.
  • Convenient for patients to use.
  • Ensure the effectiveness and shelf life of oral thin film products.
  • Oral thin film folding endurance can affect the drug release profile and efficacy. If the thin film does not maintain its structural integrity upon folding, it may affect the dissolution and absorption of the drug, ultimately affecting its therapeutic effect.

Our Oral Thin Film Folding Endurance Testing Services

Folding endurance represents the brittleness of oral thin films, the number of folds that break or have obvious creases after folding in the same position, the fewer the number of folds, the higher the brittleness of the thin film. For folding endurance testing of the oral thin film, we usually have direct testing and folding tester testing methods based on measurement purposes.

Direct Testing

For direct methods, the folding endurance evaluation is carried out manually by our professional oral thin film analysis experts.

Folding Tester Testing

To obtain repeatable and more accurate folding endurance testing results, we usually use a folding tester to complete them. Our folding tester testing process is as follows:

Fig.1 Workflow for Testing Oral Thin Film Folding Endurance.Fig.1 Process of Oral Thin Film Folding Endurance Testing. (CD Formulation)

Our Capabilities for Testing Oral Thin Film Folding Endurance

Folding Endurance Testing Detailed Information
Folding Tester Our thin film folding tester has high accuracy, stable performance, and traceable test records. It is a special instrument for measuring the folding endurance and mechanical properties of film. A folding tester usually consists of a platform or stand on which the oral thin film sample is securely placed. This instrument applies controlled mechanical forces to the film, causing it to bend and fold repeatedly in a consistent manner. The number of folds and the applied force can be adjusted under different conditions.

Our Strengths for Testing Oral Thin Film Folding Endurance

  • Our team of experienced professionals specializes in oral thin film testing and has the knowledge and skills to conduct accurate and reliable folding endurance tests.
  • We use advanced equipment and standardized testing procedures to ensure precise and consistent results.
  • We can help customers evaluate the withstand mechanical stress ability of oral thin films through thin film folding endurance testing results and guide the formulation optimization and use of oral thin films.
  • We provide detailed reports and analysis of folding endurance testing results, offering clear insights and recommendations for product improvement and optimization.

Published Data

Technology: Folding endurance testing

Journal: INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH

IF: 7.6

Published: 2013

Results: In this study, diphenhydramine hydrochloride was prepared by solvent casting method, folding endurance of the film was determined by repeatedly folding the films of uniform cross-sectional area (4*4 cm2) until it breaks. The results showed that the folding endurance of the oral thin films was found to be in the range of 35-180. The films of formulations F8, F12, F14, F15, F16, F17, Fa3, Fa5, Fa6, Fa7, Fa10, Fa12, Fa13, Fa14 showed better plasticity. The remaining formulations were found to be highly brittle.

Table.1 The folding endurance of the successful formulations. (S. Aruna Jyothi, et al., 2013)

CD Formulation uses advanced equipment and standardized procedures to provide valuable results for the folding endurance of oral thin film. If you have a requirement about our oral thin film folding endurance testing services, please contact us by phone or email, and our colleagues will reply to you within three working days.

References

  1. S. Aruna Jyothi, P. Mounika, et al. FORMULATION DEVELOPMENT AND EVALUATION OF ORAL THIN FILMS- DIPHEN HYDRAMINE HCl. INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH. 2013, Vol (4):3484-3488.
How It Works
STEP 2
We'll email you to provide your quote and confirm order details if applicable.
STEP 3
Execute the project with real-time communication, and deliver the final report promptly.
Related Services

CD Formulation, an expert in novel oral thin film delivery systems, is dedicated to supporting pharmaceutical companies in developing and commercializing innovative drug formulations...

Learn More

  • Tel:
  • Email:

Stay up to date with our latest releases of new research and promotions.

Copyright © CD Formulation. All Rights Reserved.