Oral Thin Film Adhesion Testing

One of the relatively new dosage forms for transmucosal drug delivery is the oral thin film with mucoadhesive properties. These films offer several advantages over conventional dosage forms, such as faster dissolution, higher patient compliance, and extended oral retention through reduced salivary washout. To prevent the thin film from being washed away by saliva, which could cause suffocation or failure to achieve therapeutic effects, adhesion testing becomes an important indicator for the quality control of oral thin films. CD Formulation can perform oral thin film adhesion testing using various technical methods, including texture analyzers, in vitro mucosal adhesion testing, and peel testing.

The Importance of Oral Thin Film Adhesion Testing

The oral thin film adhesion testing helps ensure that the thin film product adheres comfortably to the oral cavity, without causing discomfort or dislodging prematurely, and this is particularly important for patient acceptance and safety.

Our Oral Thin Film Adhesion Testing Methods

The oral thin film should have sufficient adhesiveness for its best performance, and this characterization is critical in the successful design and development of the oral thin film. There is currently no FDA or USP-recommended analytical procedure or standard for evaluating the adhesiveness of oral thin film. CD Formulation explores and researches oral thin film adhesion testing methods, including texture analyzers, in vitro mucosal adhesion testing, and peel testing.

Our Workflow of Oral Thin Film Adhesion Testing

Our oral thin film analysis team can respond quickly to customers' thin film adhesion testing requirements to support their oral thin film formulation development needs, and our oral thin film adhesion testing process is as follows:

Fig.1 Process of Oral Thin Film Adhesion Testing. (CD Formulation)

Adhesion Testing Methods: We offer a variety of adhesion testing methods, including texture analyzers, in vitro mucosal adhesion testing, and peel testing. We select the method that best meets the needs of our customers. These methods help us to understand the adhesion properties of the oral thin film.

Sample Preparation: We prepare samples according to the selected methods, cutting the thin films into uniform sizes and shapes to ensure consistency during testing.

Testing: We use specialized equipment to measure the adhesion of the oral thin film by quantifying the force required to detach the film from the substrate.

Data Collection and Analysis: We analyze the data to assess the adhesive properties of the oral thin film.

Report: We provide comprehensive reports detailing the adhesion testing methodology, results, and analysis. These reports can be used for regulatory submissions, quality control, and product development purposes.

Advantages of Our Oral Thin Film Adhesion Testing

• We have a complete analysis and testing service management norm and a relatively fast sample circulation cycle, and we can quickly respond to your detailed requirements for oral thin film adhesion testing within three working days.
• We have state-of-the-art adhesion testing equipment, such as high-precision texture analyzers, in vitro mucosal adhesion testing systems, etc., which can improve the accuracy and reliability of your adhesion testing.
• We offer professional analytical proposals and complimentary post-sale technical support and consulting services to assist with developing and optimizing the formulation of oral thin film drugs.

Published Data

CD Formulation has a team with rich experience providing oral thin film adhesion testing services to support your oral thin film product development. If you require our oral thin film adhesion testing services, please contact us by phone or email, and our colleagues will get back to you within three working days.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.