Oral thin films offer a convenient and easy-to-use method of drug delivery, making them particularly suitable for pediatric and geriatric populations. CD Formulation has many years of research and service experience in the development of novel drug delivery systems, we provide oral thin film efficacy evaluations that can effectively determine the therapeutic efficacy and safety of a drug for a specific disease, and by evaluating the efficacy of a drug, we can determine the effectiveness of a specific disease.

Fig.1 Development and evaluation of buccal films for treatment of oral candidiasis. (Derya Arslan, et al., 2023)

Importance of Oral Thin Film Efficacy Evaluation

Oral thin film is an increasingly popular pharmaceutical dosage form, known for its convenience, ease of administration, and rapid onset of action. The efficacy evaluation of oral thin film formulations is essential for ensuring patient safety, treatment efficacy, medication adherence, regulatory approval, and informed clinical decision-making, it provides support and basis for safe drug use in patients.

• Oral thin film efficacy evaluation is to determine the bioavailability and pharmacokinetics of the active drug ingredient.
• Oral thin film efficacy evaluation helps determine whether oral thin film is effective in treating the targeted condition or disease.
• Oral thin film efficacy evaluation helps assess any potential adverse effects, drug interactions, and toxicity.

Our Oral Thin Film Efficacy Evaluation Services

Oral thin film efficacy evaluation projects typically involve preclinical investigations, pharmacokinetic and pharmacodynamic evaluation and stability studies to determine the safety and effectiveness of the thin films.

• Preclinical Investigations: Our preclinical investigations process includes physical stability, water resistance, film thickness, folding endurance, surface pH, flavor, average weight, disintegration time, etc.
• Pharmacokinetic Evaluation: Our pharmacokinetic evaluation includes the absorption, distribution, metabolism, and excretion of thin film in the body.
• In Vitro and In Vivo Studies: Testing the performance of oral thin film in laboratory settings and in animal models can provide data on its dissolution rate, bioavailability, and efficacy in delivering the drug.
• Stability Studies: We aim to evaluate the physical, chemical, and microbiological stability of the oral films under different environmental conditions to ensure shelf life and continued effectiveness.

Our Capabilities for Evaluating Oral Thin Film Efficacy

• FT-IR study
• Mechanical properties evaluation
• Drug content and uniformity analysis
• In vitro disintegration time
• In vitro dissolution study
• Kinetic modeling of oral thin film
• Pharmacokinetic and pharmacodynamic evaluation
• Stability testing

Our Advantages in Evaluating Oral Thin Film Efficacy

• We have created an advanced oral thin film formulation development technology platform that allows us to develop high-quality oral thin film drugs.
• We conduct rigorous quality control as well as a regulatory environment throughout drug development and efficacy evaluation.
• We understand that each oral thin film formulation is unique, and we can provide tailored evaluation services to meet the specific needs and requirements of our clients.
• We work closely with our clients and provide ongoing support and communication throughout the evaluation process.

Published Data

CD Formulation insists on innovation and continuous improvement, and always remains at the forefront of the oral thin film industry. We provide reliable oral thin film efficacy evaluation services to help our customers enhance the development of oral thin film products. If you have a requirement about our oral thin film efficacy evaluation services, please contact us by phone or email, and our colleagues will reply to you within three working days.