On the basis of years of research and development (R&D) experience, the CD Formulation R&D team has established a complete liquid and semi-solid formulation platform and is committed to creating professional, quality-controllable solutions, suspension, emulsion, ointments, gel, poultices, etc., to meet different customer needs.
Both liquid and semi-solid formulations require a series of steps during the preparation process to ensure the quality and stability of the final product. The similarities and differences between them are mainly reflected in the following aspects:
CD Formulation is committed to the development and engineering research of liquid/semi-solid formulation technology platforms and has innovated and improved the standardized evaluation system for liquid and external semi-solid preparations. Our liquid/semi-solid formulation technology platform supports everything from excipient and formulation screening, process research, pilot scale-up, and industrialization, to in vivo and in vitro product evaluation.
| Technology platform | Methods |
|---|---|
| Solubilization technology | Our solubilization technology mainly uses solid dispersion solubilization technology (hot melt extrusion, spray drying, hot melt spray, etc.) to improve solubility. |
| Nanoemulsion technology |
|
| Microencapsulation technology | Our microencapsulation technology encapsulates active ingredients in protective shells, improving suspension stability and bioavailability while controlling the release of active ingredients. |
| Ion gel technology | Our ion gel technology utilizes the network structure formed by gel between solid and liquid to fix drug molecules within it, thereby stabilizing the drug content and release rate of semi-solid preparations. |
| 3D printing technology | 3D printing technology is used to precisely control the release rate and dosage of drugs in semi-solid preparations to meet individualized treatment needs. |
| Micro emulsification technology | Our micro emulsification technology uses these technologies of high-pressure homogenization, microwave radiation, ultrasonic radiation, etc., to evenly mix the oil phase and water phase to form a stable microemulsion. |
| High-shear mixing technology | Use high-shear mixing equipment to disperse and homogenize the ingredients in the suspension to ensure uniform distribution of active ingredients, achieve the required particle size distribution, and prevent particle settlement |
| Composite technology | Combining microemulsification technology, microencapsulation technology, nanotechnology and other technical means to improve the stability, permeability and release of active ingredients of emulsions and semi-solid preparations. |
In order to support the development of a variety of liquid and semi-solid formulation, our innovative sustained-release dosage platform is equipped with first-class equipment and testing instruments, including but not limited to:
CD Formulation has always been at the forefront of the development of innovative drug delivery systems. Thanks to our advanced liquid/semi-solid formulation technology platform, we provide oral liquid and external use semi-solid formulation development and production services to customers around the world. If you are interested in our services, please contact us today.
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