Liquid/Semi-Solid Drug Delivery System Development

Why Liquid/Semi-Solid Drug Delivery System Matter?

Liquid and semi-solid drug delivery systems are dosage forms that enable drugs to be administered to patients conveniently and effectively. These systems are designed to deliver the drug substance in a liquid or semi-solid form, making them easier to swallow or apply topically. Liquid drug delivery systems include solutions, suspensions, emulsions, and syrups. Semi-solid drug delivery systems include ointments, creams, gels, and lotions. These systems offer several advantages, including increased bioavailability, improved patient compliance, and reduced side effects, and are versatile and can be tailored to the specific needs of each patient, making them a popular choice for drug delivery in various therapeutic areas.

Explore Our Liquid/Semi-Solid Drug Delivery System Development Services

CD Formulation has the most advanced and comprehensive liquid and semi-solid formulation platform, including but not limited to emulsions, suspensions, solutions, gels, and other formulation forms. What makes our customers satisfied is that our innovative technology can customize the most suitable preparation form according to the characteristics and needs of their own products, thereby achieving the best effect and stability of the product. In addition, we have rich experience and resources to provide customers with one-stop services from formula design to production of preparations, ensuring that product quality and effects reach the best level.

• Formulation Design

• Active ingredient selection and formulation evaluation
• Reasonable formula design method
• Excipient characterization

• Semi-solid Dosage Forms

• Rheological characterization of semisolids
• Chemical analysis of semisolids
• In vitro performance testing

• Characterization of Liquid Dosage

• Appearance characterization
• Viscosity characterization
• Solid content characterization

Importantly, we have developed the most advanced nanoemulsion technology to produce an oil-in-water nanoemulsion. Its innovation lies in the use of minimal amounts of organic solvents and surfactants as well as excipients. This nanoemulsion can be used to develop excellent semi-solid formulations for topical use, including creams, gels, etc., thereby greatly improving bioavailability and achieving sustained and controlled release.

Professional Fields

Our Innovative Technology for Liquid/Semi-Solid Drug Delivery System Development

• Microencapsulation technology: Technology that encapsulates active ingredients in protective shells, which can improve the stability and bioavailability of suspensions. The release of active ingredients from suspensions can also be controlled.
• Nanotechnology

• Based on cholesterol-phospholipid nanoemulsions encapsulate poorly water-soluble drugs in an oil phase to improve bioavailability using very small amounts of organic solvents and surfactants to enhance efficacy.
• Polymer-based nanotechnology can encapsulate drugs in polymer mechanisms to enhance drug stability.

• Microemulsification technology: The oil phase and water phase are evenly mixed to form a stable microemulsion through high-pressure homogenization, microwave radiation, ultrasonic radiation, and other technologies.
• Emulsification technology: Drugs with poor water are made wettability into emulsions to improve the stability and solubility of the drugs and increase the bioavailability of oral liquid preparations.
• Solid dispersion technology: Disperse solid particles into the liquid phase through mechanical, chemical, or physical methods to form a uniformly dispersed liquid-solid mixture to increase the bioavailability and efficacy of oral liquid preparations. Common techniques include ball mill grinding, co-precipitation-vacuum drying, solvent-spray drying, and anti-solvent co-precipitation.
• High-shear mixing: High-shear mixing equipment is used to disperse and homogenize the ingredients in the suspension to ensure uniform distribution of active ingredients, achieve the required particle size distribution, and prevent particle settlement.
• Composite technology: Combining a variety of technical means, such as microemulsification technology, microencapsulation technology, nanotechnology, etc., to improve the stability, permeability, and release effect of active ingredients of emulsion.
• Ion gel technology: Stabilizes the drug content and release rate of semi-solid preparations by utilizing the network structure formed between solid and liquid by ion gel.

Why Choose CD Formulation for Liquid/Semi-Solid Drug Delivery System Development？

• Always at the forefront of innovative drug delivery system development and drug analysis.
• Comprehensive supporting analysis services support the development of a variety of liquid/semi-solid dosage forms, including but not limited to solution, syrup, suspension, emulsion, ointments, lniments, etc.
• A team of highly skilled scientists and researchers who has extensive experience and expertise in developing liquid/semi-solid drug delivery systems.
• Customized solutions, we work closely with their clients to understand their needs and develop tailored solutions that meet their unique specifications.
• Cutting-edge technology, we stay up-to-date on the latest advancements in the field and continuously strive to improve their techniques and processes by utilizing state-of-the-art technology and tools.
• Professional technical support and consulting services to help customers achieve their drug research and development goals.
• Cost-effective and competitive pricing.

CD Formulation is at the forefront of the development of innovative drug delivery systems, providing customized solutions for liquid/and semi-solid formulations. Our advanced technology and equipment, coupled with our commitment to precision and efficiency, make us a reliable partner for advancing innovative systems. Please contact us today to discover how you can improve drug stability and enhance efficacy with our liquid/semi-solid formulation platforms.