Liposome Size Distribution Testing

At CD Formulation, our liposomal particle size distribution analysis center utilizes a range of state-of-the-art detection technologies and equipment to ensure accurate and efficient measurement of particle size distribution, catering to the diverse needs of our clients. Our team comprises seasoned experts who are dedicated to providing unparalleled professional support and analysis services, regardless of whether you operate in the food, pharmaceutical, or cosmetic industry.

The Importance of Testing Liposome Size Distribution

The size of liposomes plays a crucial role in determining the drug-loading capacity, degree of aggregation, deposition status, circulating lifetime and tissue permeability of liposome drugs. Generally speaking, smaller-sized liposome drugs exhibit higher drug-loading capacity, lower degree of aggregation, better deposition status, longer circulating lifetime and greater tissue permeability. Therefore, it is essential to ensure that the particle size of liposome drugs falls within the prescribed range and remains consistent throughout their shelf life.

What Can We Do About Liposome Size Distribution Testing?

Generally, the average particle size of liposomes ranges from 100 to 240 nm depending on the liposome preparation method employed. Currently, in our liposome particle size analysis test center, various techniques are available for assessing liposome size, including dynamic light scattering (DLS), nanoparticle tracking analysis (NTA), transmission electron microscopy (TEM), cryo-electron microscopy (cryo-EM), atomic force microscopy (AFM), and single particle optical sensing technology (SPOS). Among these methods, DLS is widely utilized as a simple, rapid, non-invasive analytical technique for measuring submicron-sized liposomes while also enabling potential detection. SPOS is specifically employed for sizing liposomes larger than 1 μm.

• Screening of detection methods. Different detection methods have their advantages and disadvantages, choosing the right detection method is the first step in the completion of particle size distribution detection, but also an important step.
• Screening of test conditions and parameters. The selection of test conditions and parameters such as temperature, pH, ionic strength, dispersion medium, etc. is also crucial, which may directly affect the test results.

Our Technologies for Testing Liposome Size Distribution

Our Advantages in Testing Liposome Size Distribution

• Specialty. We possess professional physical and chemical analysis talents and teams.
• Unique Analytics Platform. The analysis service platform caters to the diverse requirements of various projects.
• Rapid turnaround time. Our services allow us to customize them according to the unique requirements of each client.

Published Data

The CD Formulation team utilizes cutting-edge technology and state-of-the-art equipment for conducting thorough and expert analysis of size distribution of liposomes, catering to the needs of our esteemed clientele. If you require further information regarding our extensive array of services, please feel free to contact us.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.