Transdermal preparation refers to the dosage form that is administered through the skin surface, so that the drug passes through the skin at a constant speed or near a constant speed, and then absorbs into the systemic circulation to play a local or systemic therapeutic effect. Since the drug does not pass through the gastrointestinal tract, the transdermal drug delivery system has the advantages of avoiding the influence of pH and transport enzymes in the digestive tract, and avoiding the first pass effect of the liver, ensuring the drug concentration and controlling the drug delivery speed, so as to maintain a constant blood drug concentration and reduce the frequency of administration, thereby improving the adaptability of patients. It has a good application prospect. The CD Formulation analysis center is capable of providing comprehensive, professional skin diffusion studies for liposomal transdermal products.

Why You Need Liposome In Vitro Transdermal Diffusion Study?

A drug in a transdermal preparation can only be effective after it enters the systemic circulation through the skin. Skin is the rate-limiting barrier for transdermal absorption of drugs, so the efficiency of the drug passing through the skin directly affects the quality and effectiveness of the preparation. Therefore, the drug diffusion efficiency is not only an important indicator of the quality control of the preparation, but also an internal guarantee of the effectiveness of the drug.

Explore Our Services for Liposome In Vitro Transdermal Diffusion Study

Screening of Transdermal Diffusion Devices

At present, there are 3 kinds of transdermal diffusion experimental devices provided by us, which are horizontal diffusion cell Valia-Chien cell, vertical Franz diffusion cell and flow cell. Franz vertical diffusion cell is the main method.

Selection of Absorbing Medium

Our absorption medium is specifically formulated to closely mimic bodily fluids, such as physiological saline or a pH 7.5 phosphate buffer solution. In the event that the drug exhibits limited solubility in these media, there is a possibility of saturation during diffusion, resulting in decelerated or halted transdermal penetration. Under such circumstances, it is recommended to substitute the absorption medium with fresh media or incorporate suitable surfactants.

Selection of Skin Types

We provide human skin, animal skin, artificial composite membrane for customers to choose.

Our Platforms for Liposome In Vitro Transdermal Diffusion Study

Highlights for Liposome In Vitro Transdermal Diffusion Study

• Advanced techniques. We have our screening of transdermal diffusion platforms and we combine multiple technologies such as: CAMVA, ICE test, RhCE EIT, FL test method, etc.
• Unique. Independent project management system for liposome in vitro transdermal diffusion study, each project has its own folder.
• Efficiency. The study reports and results are delivered to customers quickly and efficiently throughout the process.
• Top equipment. Our lab is equipped with fourier transformInfrared spectroscopy, coherent Anti-Stokes raman scattering, surface-enhanced raman scattering, stimulated raman scattering, and so on.

Published Data

CD Formulation's liposome in vitro transdermal diffusion study service is designed to provide comprehensive analytical services to our clients. If you need any kind of assistance, please contact us immediately.