Custom Magnetically Responsive Liposome Service

Magnetically responsive liposomes, comprising magnetic nanoparticles encapsulated within liposomes, are acknowledged for their versatility in drug and gene delivery, cancer diagnosis, and treatment. With their chemical functionality, biocompatibility, and potential for cancer hyperthermia therapy, they represent a groundbreaking delivery system. As a contract service provider, CD Formulation leverages advanced technology and expertise to engineer customized magnetic nanoparticle delivery systems, focusing on magnetic liposomes.

What are Magnetically Responsive Liposomes?

Magnetic-targeted liposomes use magnetic material to guide active substances into specific tissues, increasing drug concentration in the target area. Releasing drugs through the use of magnetic fields becomes possible by incorporating magnetic nanoparticles such as iron oxide nanoparticles (IONPs). The process involves exposing the MNP-loaded liposome system to alternating magnetic fields (AMF) to trigger drug release via a thermal process generated by the MNPs. Magnetically nanoparticles can be arranged differently in the structure of liposomes depending on the nature of their surface.

Fig.1 Schematic illustration of magnetoliposomes as magnetically assisted drug nanocarriers. (Edyta Maroń, et al., 2023)

Our Magnetically Responsive Liposome Customization Service

Synthesis of magnetic nanoparticles service

Magnetically responsive liposomes are generated through the combination of drug-loaded liposomes with a lipid mixture, followed by coating them with magnetic nanoparticles. We offer a bottom-up method (construction of nanostructures by individual atoms or molecules), as well as a top-down method for developing magnetic liposomes, including (grinding microstructures down to the nanoscale).

Magnetically responsive liposome customization service

Magnetically responsive liposomes are incorporated with magnetic carrier materials, such as magnetic Fe₃O₄, with a directional effect on the lesion site under the action of an external magnetic field, because of their good drug-carrying and targeting properties. At present, we can customize magnetic liposomes, including As₂O₃ nanomagnetic liposomes, Mn_xZn_(1-x)Fe₂O₄ magnetic liposomes, multi-response stimulation liposomes, paramagnetic long cycle nanoliposomes, a variety of modified magnetic liposomes, etc.

Magnetically responsive liposome modification service

We can provide a series of modification services, including modification with chitosan, mannitol, and cell-penetrating peptide (TAT).

Fig.2 Schematic diagram of our workflow. (CD Formulation)

Our Platforms for Magnetically Responsive Liposome Customization

We have established a proprietary platform for the development of magnetically responsive liposomes and can offer the following technologies:

Why Choose CD Formulation?

• Proficient teams. Our research team comprises a cohort of proficient scientists specializing in immunology, medicine, biology, and other related disciplines. They possess extensive expertise in the development of biological delivery systems, particularly focusing on magnetically responsive liposome delivery systems.
• First-class magnetic liposome development techniques. We utilize a range of techniques to tailor liposomes according to our specific magnetic sensitivity requirements, including the application of thermal-magnetic combined therapy technology and the development of long-lasting paramagnetic liposomes.
• Customized diversification. Our magnetic response liposome products can be customized to meet the research and application requirements of various industries, incorporating multiple stimulation-response mechanisms such as medical research, drug delivery systems, contrast agent development, biosensors, cell research, biomedical applications, agriculture, and botany.

Published Data

CD Formulation has established a dedicated platform for magnetically response liposomes to offer our customers a substantial quantity of sensitive liposome products. Please feel free to contact us if you need any assistance.

How It Works

STEP 1

Submit a service request describing your specific research or development need.

STEP 2

We'll email you to provide your quote and confirm order details if applicable.

STEP 3

Execute the project with real-time communication, and deliver the final report promptly.