Peptide & Protein Liposome Development

As biotechnology develops rapidly today, liposomes are gradually going from strength to strength in terms of preparation methods, production processes, and administration routes, and their uses are becoming more widespread. CD Formulation is a leading biologics company developing innovative drug delivery solutions. Our peptide and protein liposome development services harness the power of liposomes to improve the delivery and efficacy of therapeutic biomolecules.

Applications of Liposomes in Drug Delivery

A lipid bilayer forms the structure of liposomes, nanoscale vesicles with a similar structure to the membranes of human cells. Hydrophilic and hydrophobic molecules can be encapsulated within their lipid bilayers and aqueous cores, respectively, in the field of drug delivery. As drug carriers, liposomes have a variety of advantages, including improving stability and targeting. Through our services, you can use liposomes to accurately deliver peptides and proteins to their target sites, thereby increasing bioavailability and reducing drug toxicity.

Types of Peptide & Protein Liposomes We Can Develop

• Conventional Liposomes

Classic liposomes consist of phospholipid bilayers encapsulating therapeutic peptides and proteins.

• Stealth Liposomes

Surface-modified liposomes with polyethylene glycol (PEG) coating prolong circulation time and reduce clearance by the immune system.

• pH-Sensitive Liposomes

Liposomes are designed to release their cargo in response to changes in pH, such as the lower pH found in tumor tissues.

• Targeted Liposomes

Liposomes modified with ligands or antibodies to specifically recognize and bind to target cells, enhancing selective delivery and reducing off-target effects.

Our Peptide & Protein Liposome Development Process

Advantages of Our Peptide & Protein Liposome Development Service

• We continue to optimize liposome preparation methods and achieve high encapsulation rates of up to 95%, which can improve the bioavailability of peptides and proteins.
• Our expertise in surface modification technologies, including the use of specific ligands and antibodies, enables the precise targeting of liposomes to the desired cells or tissues.
• We are able to precisely control the size of liposomes (ranging from 50 to 200 nm), ensuring optimal cellular uptake and efficient drug delivery.
• We use state-of-the-art analytical techniques such as dynamic light scattering (DLS) and transmission electron microscopy (TEM) to ensure consistent size distribution, surface charge, and encapsulation efficiency to provide reliable and repeatable results.
• We can use freeze-drying and rehydration techniques to extend product shelf life and enable room temperature storage.

At CD Formulation, we're devoted to progressing drug delivery through innovation. Our advanced expertise lies in custom liposomal formulations for peptides and proteins. Talk to our formulation specialists, and we'll listen closely to characterize your unique needs, then leverage cutting-edge tools to develop just the right lipid-based carrier system. Contact CD Formulation today to explore the possibilities!