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CD Formulation is committed to using advanced nanotechnology to provide innovative solutions to the global pharmaceutical industry. Our core business is the development of high-quality gold nanoparticles for drug delivery. These particles offer significant advantages in the delivery, stability, and efficacy of peptides and proteins. Our services include full tracking from particle design and production to application testing to ensure customers receive the highest quality products.
Gold nanoparticles are nanomaterials with excellent physical and chemical properties, and their applications in the medical field have attracted widespread attention. We exploit the unique properties of gold nanoparticles, such as high electron density, surface plasmon resonance effect, etc., making them ideal carriers for drug delivery. We can also functionally modify gold nanoparticles according to customer needs to achieve precise delivery of peptides and proteins in the body.
Formation and mechanism of action - BH3 peptide gold nanoparticles (Zhang X.; et al. 2023)
We can design gold nanoparticles with surface modifications, attach peptide or protein modifications to the gold nanoparticle surface, or polyethylene glycol to improve stability, extend circulation time, and facilitate targeted delivery to specific cells or tissues.
We develop hollow gold nanoparticles with a unique structure that allows for the encapsulation of therapeutic peptides and proteins within the hollow core. This design offers enhanced payload capacity and controlled release capabilities.
Our expertise extends to the development of gold nanorods, which possess unique optical properties and can be utilized for both drug delivery and imaging applications. Surface modifications enable targeted delivery and imaging of peptides and proteins.
Evaluate and select gold core size, shape, and surface coatings to match delivery requirements.
Conjugate targeting ligands, stabilizing polymers, and stealth coatings onto the gold surface.
Develop optimized loading methods to adsorb, entrap, or covalently bind the peptide/protein onto the nanoparticle matrix.
Use TEM, DLS, ZETA potential, FTIR, ICP-MS, and other techniques to comprehensively analyze quality attributes.
Apply stabilizing excipients and delivery-enhancing strategies to improve pharmacokinetics and efficacy.
Refine and scale up manufacturing methods from benchtop to cGMP processes ensuring quality and batch consistency.
Through relentless research and application of cutting-edge methods, CD Formulation is driven to develop more ingenious solutions empowering global healthcare. Whether exploring novel targets or scaling established formulations, collaborating with our gold engineering experts can streamline progress. Interested in how working together might benefit your peptide, protein or other biologic objectives? Contact us and let's set up an exploratory consultation.
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