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Nanoparticle Development for Peptide & Protein Delivery

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In the realm of biotechnology, the delivery of peptides and proteins poses a unique challenge due to their fragile nature and susceptibility to degradation. To overcome these obstacles, CD Formulation, a leading biologics company, specializes in the development of nanoparticles for the delivery of peptides and proteins. With our cutting-edge technology and expertise in nanoparticle development, we offer comprehensive services to revolutionize drug delivery in the biopharmaceutical industry.

Why are Nanoparticles Used to Deliver Peptides and Proteins?

Peptides and proteins are important active substances in living organisms and have extremely high pharmacological effects and biological activities. However, due to their molecular size and chemical properties, effective delivery is difficult through conventional methods. As an advanced drug delivery carrier, nanoparticles can encapsulate biological agents and change the pharmacokinetic properties of peptides and proteins.

Nanoparticles for Peptides and Proteins Delivery (Pudlarz A.; et al. 2018)Nanoparticles for Peptides and Proteins Delivery (Pudlarz A.; et al. 2018)

How Do We Develop Nanoparticles for Peptide & Protein Delivery?

  • Customer Needs Analysis

    Communicate in depth with customers to understand their specific needs and requirements.

  • Formulation Design

    Develop detailed development plans based on customer needs and project goals.

  • Experimental Preparation

    Through laboratory research, we prepare peptide and protein delivery nanoparticles that meet customer needs.

  • Quality Inspection

    Conduct comprehensive quality testing on the prepared nanoparticles, including particle size, potential, stability and other indicators.

  • Formulation Optimization

    Based on the quality test results, the nanoparticle formula is optimized to improve its performance and stability.

  • Animal Experiment

    After confirming that the nanoparticle formula is basically stable, animal model experiments are conducted to evaluate its efficacy and safety.

Our Nanoparticle Development Technology Platforms

  • Nanoparticle Synthesis

We utilize various synthesis methods, such as solvent evaporation, emulsion techniques, and self-assembly processes, to fabricate nanoparticles with precise control over their physical and chemical properties.

  • Surface Modification

We specialize in surface modification techniques like ligand conjugation, PEGylation, and bioconjugation, enabling us to tailor nanoparticles for specific targeting, improved stability, and enhanced cellular uptake.

  • Characterization and Analysis

We employ a range of advanced analytical techniques, including dynamic light scattering (DLS), transmission electron microscopy (TEM), and Fourier-transform infrared spectroscopy (FTIR), to comprehensively characterize the size, morphology, stability and drug-loading capacity of our nanoparticles.

  • In Vitro and In Vivo Evaluation

Our team conducts extensive in vitro and in vivo studies, employing cell-based assays and release kinetics analysis, to evaluate the efficacy and safety of our nanoparticle formulations.

Applications of Our Nanoparticle Development Services

  • Cancer Therapeutics

Our nanoparticle-based delivery systems can effectively deliver therapeutic peptides or proteins directly to the tumor site while minimizing systemic side effects.

  • Vaccines

Our nanoparticle formulations can enhance the stability, immunogenicity, and targeted delivery of peptide or protein-based vaccines, improving the efficacy of immunization strategies.

  • Regenerative Medicine

Nanoparticles can be utilized to deliver growth factors, cytokines, and other bioactive peptides or proteins, promoting tissue regeneration and accelerating wound healing processes.

  • Central Nervous System Disorders

Our specialized nanoparticle systems can overcome the blood-brain barrier, facilitating the delivery of peptides or proteins for the treatment of neurological disorders.

Advantages of Our Peptide & Protein Nanoparticle Development Services

  • We're constantly staying on top of the latest nanotech innovations so we can offer cutting-edge solutions.
  • Using nanoparticles as carriers, peptides and proteins can be protected from damage by the internal environment while improving the bioavailability and targeting effect of drugs.
  • We provide customers with a series of comprehensive services including peptide and protein screening, preparation, quality testing and efficacy evaluation.
  • Customers can rest assured knowing their valuable ideas and info are kept confidential under our tight intellectual property policies.
  • Our researchers are dedicated to discovering and refining environmentally friendly nanomaterials and techniques.

CD Formulation is at the forefront of nanoparticle-based drug delivery, specializing in the development of tailored solutions for peptide and protein delivery. Our comprehensive services, state-of-the-art technology platform, and dedication to quality and innovation make us the ideal partner for your nanoparticle development needs. Contact us today to discuss your specific requirements!

Reference

  1. Pudlarz A.; Szemraj J. Nanoparticles as carriers of proteins, peptides and other therapeutic molecules. Open Life Sci. 2018, 13:285-298.
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