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CD Formulation is equipped with advanced next generation sequencing (NGS) platforms, advanced technology and expert scientists to provide a wide range of genomic solutions to meet your diverse research objectives and budgets. Our service model is very flexible and can be tailored to your project needs.
As we all know, the genetic material of human beings is DNA. Simply, genomics is the study of whole genomes of organisms, and incorporates elements from genetics. Genomics uses a combination of recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyse the structure and function of genomes[1]. To study the genome, the first task is to sequence and assemble the genes to complete the genome sequence map, and next decipher the resulting sequence map.
With the development of various technologies, the research methods of genomics are becoming more and more diversified, and genomics research mainly based on sequencing is becoming more and more widespread. It is applied in various fields of human social development including:
Plant and animal breeding
Population genetic evolution research
Crop cultivation
Genetic mapping
Genome genetic diversity research of core germplasm resources
Genome-wide association study
Rapid and accurate detection of mutation site
Genetic engineering drug development
Gene sequencing technology is a method used to determine the sequence of DNA. From the original Sanger method sequencing, to the later NGS, and now single molecule sequencing technology, advances in sequencing technology have driven advances in genomics, biomedical research, and clinical diagnostics. We offer a variety of genome sequencing services, as described below.
Target region sequencing
Target region sequencing (TRS) is a detection method that designs a specific probe for the genomic region of interest[2]. The method can obtain the sequence information of the specified target region, which significantly reduce the research cost and improve the research efficiency of the specific target region. Applications of TRS include: cancer research; human population studies; linkage analysis for inherited diseases; detection and quantification of low-frequency alleles and rare variants,detection of somatic and germline mutations,discovery of biomarkers and therapeutic targets.
Whole exome sequencing
The human exome region accounts for only 1%-2% of the total genome sequence[3], but it contains 85% of disease-causing mutations, and mutations in the coding region often lead to serious consequences[4]. Compared with whole genome sequencing, whole exome sequencing (WES) is more cost-effective. It has high throughput, higher detection rate, and closer to correct diagnosis results compared with karyotyping, chip, and Sanger sequencing.
Human whole genome sequencing
Human whole genome sequencing (WGS) is a method of sequencing the entire genome of an individual or population based on the human genome reference sequence and analyzing it at the individual or population level[5]. WGS can more comprehensively explore gene sequence differences and structural variations, and can be used for gene diversity analysis, genetic evolution analysis, disease and susceptibility gene screening, etc., which has become one of the most rapid and effective methods in the field of human genetics, translational medicine and population evolution.
Whole genome resequencing
Whole genome resequencing (WGR) refers to sequencing the entire genome sequence of different individuals of a species on the basis of the known genome sequence of the species, and analyzing the differences of individuals or groups [1]. Full genetic information can be obtained, and each base sequence can be analyzed accurately and comprehensively.
Genome chip technology, also known as DNA Microarray[6] , DNA chip, and oligonucleotide array, a kind of rapid, accurate and efficient detection of biological samples based on the principle of hybridization sequencing. We offer a variety of genome chip services, including:
Affymetrix Chip
Illumina Chip
Agilent Chip
Expertise: Our experienced scientists, laboratory technicians and bioinformaticians with a wealth of knowledge expertise in the latest technologies and methods. We offer accurate and reliable analysis to customers.
Customization: Our teams work closely with customers to understand their research needs and design custom solutions.
Quality: Our teams adhere to strict quality control measures throughout the workflow to ensure accurate and consistent data generation.
Speed: We offer high-efficient service.
Comprehensive capabilities: Industry-leading equipment allows us to offer comprehensive capabilities to meet extensive of research needs.
Data support: Our bioinformatics team provides expert data analysis and interpretation to ensure that our clients obtain meaningful insights from data.
Welcome to learn more about the options available to you and consult with experts about solutions for your projects.
For Research Use Only. Not for use in diagnostic procedures.
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