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CD Formulation provides comprehensive antiserum preparation services, including antigen preparation, immune injection, antibody extraction and serum preparation. Our team consists of a group of experienced and professional personnel with deep knowledge and skills in immunology, biomedicine and other fields, who can provide customers with personalized solutions.
Antiviral serum is a specialized therapeutic product that contains a concentrated mixture of antibodies specifically designed to target and neutralize viral pathogens. The antibodies present in antiviral serum, also known as antiviral antibodies or neutralizing antibodies, are capable of binding to and inhibiting the replication of specific viruses, thereby preventing viral entry, spread, and infection within the body. Antiviral serum plays a vital role in passive immunization, where preformed antibodies are administered to provide immediate protection or aid in the recovery from viral infections.
At CD Formulation, we use the most advanced immunological technologies and methods to extract high-quality antibodies from animals vaccinated with specific immunization procedures. Our preparation process strictly follows international biosafety and quality control standards to ensure the safety and quality of all products. Through our preparation technology, we can provide customers with efficient and stable antiviral serum.
Choosing the optimal animal species is critical when preparing antiviral serum. Key considerations include phylogenetic relatedness to viral targets, required serum quantity and quality, and host responsiveness. Our most commonly used experimental animal is the rabbit, but other animals such as sheep, horses, chickens, monkeys, and guinea pigs are also among our alternatives.
According to the nature of the antigen and the required amount of immune serum, we first prepare the antigen solution. Dilute the antigen to 2 mg/ml with sterile physiological saline, add penicillin and streptomycin, and leave it at 4°C overnight. Take it out the next day and mix it with adjuvants to make an emulsion for animal immunization.
The immunization dose for each animal is determined based on factors such as the antigenicity, molecular weight, individual status of the animal, and immunization time. Generally speaking, the first dose of antigen is 50-100 μg/time for mice, 100-200 μg/time for rats, and 100 μg-1 mg/time for rabbits. The synthetic immunogen is 2 mg (hapten is about 20-200 μg), which generally needs to be mixed with an equal amount of Freund's complete adjuvant. The dose for boosting immunity is 1/2 of the initial dose, usually with incomplete Freund's adjuvant or no adjuvant.
The blood of the immunized animals is extracted, and serum products are prepared through virus inactivation and other means.
At CD Formulation, we're obsessed with developing antiviral serums packed with targeted, potent antibodies. Our serum prep service is meticulous, we carefully select antigens, pick the optimal animal hosts, immunize and boost on schedule, monitor titers, purify, formulate, and rigorously test every batch. Viral threats are constantly evolving, but our antiviral serums evolve right along with them. Let's discuss your project and how we can rapidly develop a high-titer serum tailored to your needs!