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Antibody Nanoparticle Development

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Antibody Nanoparticle Development

Due to their unique mechanism of action and high efficacy, antibody drugs have become a global center for research and development in the treatment of malignant tumors and autoimmune diseases. Furthermore, antibodies are polar compounds that have limited transmembrane properties and have a large relative molecular mass. There are some particularities and complexity to the pharmacokinetics of antibodies. As new delivery systems are developed for drugs, nanoparticles have broad potential for antibody delivery applications.

CD Formulation has a series of high-performance innovative antibody preparation product, including antibody nanoparticle preparation materials with various functions. We can provide professional antibody nanoparticle preparation services and provide strong support for the life sciences and medical research, as well as the pharmaceutical industry.

How to Develop Antibody Nanoparticle?

Based on your requirements, CD Formulation offers custom services for polymer nanoparticles in a variety of materials. Our experts have extensive experience in the preparation of nanoparticles such as polymeric micelles, lipid nanoparticles (LNP), liposomes, polymeric nanoparticles, albumin nanoparticles, nanoemulsions, gold nanoparticles and nanographene. Through the rational assembly and functionalization of nanoparticles, we realize the design of multifunctional antibody nanoparticles through size control, rational drug loading, active targeting strategies, surface modification, slow and controlled release, etc.

Our Technology Platforms for Antibody Nanoparticle Preparation

CD Formulation has successfully built a professional nanomedicine preparation technology platform with years of research and development experience, which can carry out targeted delivery of small molecule chemical drugs, macromolecule protein drugs, RNA and other nucleic acid drugs, and realize multifunctional nanodrug design.

  • Liposome technology platform
  • Polymer micelles/capsules technology platform
  • Polymer nanoparticle technology platform
  • Nanoemulsion technology platform
  • Magnetic lipid nanoparticle technology platform
  • Gold nanoparticles (spherical particles, gold nanorods, gold nanocages) technology platform
  • Nano graphene technology platform
  • Smart gel technology platform

Featured Nanoparticles for Antibody Delivery

As drug carriers, polymer nanoparticles have the advantages of good stability and high drug loading capacity. They can be actively targeted at specific organs, tissues and cells through modification. At CD Formulation, we commonly use polyester materials such as polylactic acid (PLA), polylactic acid-co-glycolic acid (PLGA), and polycaprolactone (PCL) to prepare nanoparticles because these polymer materials are non-toxic, and biodegradable. You can choose any carrier on our nanoparticle preparation technology platform according to your own interests, or you can directly let us customize a one-stop solution for you.

Hydrogels have been widely used in the biomedical field due to their good biocompatibility, shaping ability and performance characteristics similar to extracellular matrix. Our company provides various types of hydrogel preparation services, which can help you achieve sustained and controlled release of antibodies.

  • Environmentally Sensitive Hydrogels: Temperature/ pH / Ion / Light / Enzyme / Magnetic / Redox Sensitive Hydrogels
  • Multi-sensitive hydrogel
  • Biodegradable hydrogel

Our Process of Antibody Nanoparticle Development

  • Feasibility Demonstration
    • The client puts forward specific needs
    • CD Formulation presents a feasibility report through technical demonstration
    • We will formulate product development plans, time calculations and budgets
  • Development Phase
    After we reach a cooperation agreement with our customers,
    • We develop and develop according to the established plan
    • We will record the experimental data generated during the project development process in detail
    • We will regularly report the project development progress and experimental results to the client

  • Product Trial Production
    For customers with large product demands,
    • We will formulate product production and quality inspection procedures
    • We will provide sample products to the client for testing
  • Project Closure
    • Our company provides products in the quantities required by the client
    • We provide a complete project research and development report, including experimental principles and methods, repeatable experimental procedures, experimental difficulties and precautions, etc.

Highlights of our Antibody Nanoparticle Customization Services

  • Our nanoparticle preparation technology can enhance the stability and bioavailability of antibodies.
  • By exploiting the unique properties of nanoparticles, we can precisely deliver antibodies to specific sites of action, enhancing therapeutic efficacy while minimizing off-target effects.
  • Our services are designed to accommodate manufacturing of all sizes, from small research quantities to large-scale production.

CD Formulation's biologics R&D team has extensive experience in biologics R&D, including monoclonal antibodies, recombinant proteins, peptides and genetic drugs, etc. Our team of skilled scientists and engineers is committed to delivering customized antibody nanoparticle formulations tailored to meet your specific research and therapeutic needs. By harnessing the power of nanotechnology, we can enhance the stability, bioavailability, and targeting capabilities of antibodies, unlocking their full potential for effective disease treatment. If you have relevant needs, please feel free to contact us!

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