Antibody Cocktail Therapy Development
InquiryAs an innovative enterprise focusing on the field of biomedicine, CD Formulation has been committed to developing and providing more efficient and safer drug therapies. With years of expertise and a multidisciplinary team of renowned scientists, we have become a leader in the development of cutting-edge biologics. Leveraging state-of-the-art facilities and cutting-edge technologies, our antibody cocktail therapy development services can provide clients with solutions tailored to meet their unique needs.
What is Antibody Cocktail Therapy?
Antibody cocktail therapy is a treatment that mixes two or more monoclonal antibodies together. By combining the properties of different antibodies, this therapy can target multiple targets simultaneously, thereby enhancing the effectiveness of treatment and reducing the development of drug resistance. Antibody cocktail therapy has broad application prospects in fields such as tumors and autoimmune diseases.
How to Develop Antibody Cocktail Therapy?
The development of antibody cocktails is a complex and meticulous process that requires a deep understanding of target biology, antibody engineering, and combinatorial approaches. At CD Formulation, we employ a comprehensive and systematic development process.
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Project Initiation
According to the needs of customers, we first need to determine the indications and market demand for antibody cocktail therapy and clarify the treatment targets.
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Target Identification and Validation
Our experts conduct thorough research and analysis to identify suitable disease targets, considering their relevance, therapeutic potential and feasibility of antibody-based intervention.
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Antibody Preparation
You can choose to provide the antibodies yourself. Please ensure that the amounts of antibodies are sufficient to meet the needs of the experimental design. You can also tell us the sequence of your target antibody and let us prepare the antibody for you.
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Antibody Cocktail
Depending on the therapeutic target, we combine monoclonal antibodies with different properties to form antibody cocktails. We will consider factors such as antibody ratio, affinity and half-life when combining.
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In Vitro and in Vivo Assessment
We can evaluate for you the functional properties of your selected antibodies in a variety of in vitro and in vivo models, including neutralizing capacity, effector function, and safety.
Our Technology Platforms for Antibody Cocktail Therapy Development
The development of antibody cocktail therapy requires the support of multiple technology platforms.
- Antibody Screening Platform
This platform uses a series of cell biology, immunology and genetic engineering techniques to screen monoclonal antibodies with high affinity and specificity from immunized animals or cell lines.
The cell culture platform provides a large number of cell lines and cell lines for the development of antibody cocktail therapies for the preparation and production of antibodies, as well as in vitro functional evaluation of antibodies.
- Protein Purification Platform
CD Formulation's experts master a variety of protein purification methods, such as ion exchange, gel filtration, and hydrophobic interaction, to separate and purify antibodies to improve their purity and quality.
We use a series of detection technologies, including HPLC, SDS-PAGE, Western blot, etc., to strictly test and evaluate the production process and product quality of antibody cocktail therapies.
Advantages of Our Antibody Cocktail Therapy Development Services
- We have an experienced team and technical support team.
- We focus on technological innovation and independent research and development, have a variety of technology platforms and production processes, and can carry out customized development according to customer needs.
- We are able to respond quickly and are highly flexible, able to adjust our plans promptly according to market changes and customer needs.
- We have established a complete quality control system to ensure the stability and reliability of every link.
The systematic antibody cocktail therapy development services provided by CD Formulation help customers develop efficient and safe antibody cocktail therapies through professional team support, technological innovation and flexibility, complete quality control system and all-round services. If you have any questions or need to inquire, please call us or send an email. We will serve you wholeheartedly!
References
- Focosi D.; et al. A critical analysis of the use of cilgavimab plus tixagevimab monoclonal antibody cocktail (Evusheld™) for COVID-19 prophylaxis and treatment. Viruses. 2022, 14(9):1999.
- Crunkhorn S.; et al. Antibody cocktail eliminates ebolaviruses. Nat Rev Drug Discov. 2022, 21(5):335.
- Kakinoki Y.; et al. Impact of antibody cocktail therapy combined with casirivimab and imdevimab on clinical outcome for patients with COVID-19 in a real-life setting: a single institute analysis. Int J Infect Dis. 2022, 117:189-194.
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